![]() ![]() The SARS-CoV-2 virus can be mapped out similar to a family tree. As genetic changes happen over time, the virus that causes COVID-19 begins to form genetic lineages. What You Need to Know About Variants | View Transcript Īs a virus spreads, it has a chance to change. Those variants must be monitored more carefully. Some variations allow the virus to spread more easily or make it resistant to treatments or vaccines. These small differences, or variants, have been studied and identified since the beginning of the pandemic. By comparing the branches, scientists can label them according to the differences. doi:10.1001/ you think about a virus like a tree growing and branching out, each branch on the tree is slightly different than the others. Incubation period of COVID-19 caused by unique SARS-CoV-2 strains: A systematic review and meta-analysis. JAMA Network Open. 2022 5(8):e2228008. Wu Y, Kang L, Guo Z, Liu J, Liu M, Liang W.The pooled incubation period of COVID-19 in this study was 6.57 days.” The pooled incubation period of different variants is a key factor in determining the isolation period. “Although variants such as Alpha, Beta, and Gamma are currently only prevalent in a few countries in Southeast Asia, South America, and Africa, the Delta and Omicron variants have become the dominant strains in many countries around the world,” the researchers wrote.“Identifying the incubation period of different variants is a key factor in determining the isolation period. Urgent timelines resulted in estimations of incubation periods in limited case numbers. And third, there were not many studies on incubation periods caused by SARS-CoV-2 variants. This resulted in the assumption that incubation periods were consistent across different populations. Second, the data collected was diverse in study population, data collection periods, and methods of analysis. As most of this data was collected retrospectively, recall bias is possible. First, to determine incubation periods, knowledge of exposure to the virus and onset of symptoms were necessary. Taken together, these findings suggest a mean COVID-19 incubation period of 6.57 days-longer than those of other acute respiratory viral infections like the human coronavirus, influenza A, parainfluenza, respiratory syncytial virus, and rhinovirus. The incubation period for the Alpha variant of COVID-19 was 5 days while the Beta variant was 4.5 days, the Delta variant was 4.41 days, and the Omicron variant was 3.42 days. Most studies were conducted in China between January and March 2020.Īcross these studies, the pooled incubation period was 6.57 days, with results ranging from 1.80 to 18.87 days. ![]() Of the 142 studies, 45 were strong, 82 were moderate, and 15 were weak. Investigators conducted a meta-analysis of 142 studies including 8112 patients with COVID-19. Researchers have conducted several studies to find the average incubation period of COVID-19 however, the evolution of different SARS-CoV-2 variants has made it increasingly difficult. Consistent evolution and mutation of the SARS-CoV-2 virus throughout the pandemic has highlighted the importance of identifying the incubation period of variants, according to research results published in JAMA Network Open. ![]()
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